Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia cellsGITENDRA WICKREMASINGHE, R; GANESHAGURU, Kanagasabai; MEHTA, Atul B et al.British journal of haematology. 2001, Vol 114, Num 3, pp 608-615, issn 0007-1048Article

The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma linesJULIEN GRILLE, Sylvia; BELLACOSA, Alfonso; UPSON, John et al.Cancer research (Baltimore). 2003, Vol 63, Num 9, pp 2172-2178, issn 0008-5472, 7 p.Article

Simvastatin induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic isletsCONTRERAS, Juan L; SMYTH, Cheryl A; BILBAO, Guadalupe et al.Transplantation. 2002, Vol 74, Num 8, pp 1063-1069, issn 0041-1337Article

Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-κB and tumor progressionDHAWAN, Punita; SINGH, Amar B; ELLIS, Darrel L et al.Cancer research (Baltimore). 2002, Vol 62, Num 24, pp 7335-7342, issn 0008-5472, 8 p.Article

Ultraviolet-induced phosphorylation of p70^S6K at Thr³⁸⁹ and Thr⁴²¹/Ser⁴²⁴ involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C¹CHUANSHU HUANG; JINGXIA LI; QINGDONG KE et al.Cancer research (Baltimore). 2002, Vol 62, Num 20, pp 5689-5697, issn 0008-5472, 9 p.Article

Survival-signaling pathway as a promising target for cancer chemotherapyFUJITA, Naoya; TSURUO, Takashi.Cancer chemotherapy and pharmacology. 2003, Vol 52, pp S24-S28, issn 0344-5704, SUP1Conference Paper

14-3-3 Interacts with the tumor suppressor tuberin at Akt phosphorylation site(s)LIU, Matt Y; CAI, Shengli; ESPEJO, Alexsandra et al.Cancer research (Baltimore). 2002, Vol 62, Num 22, pp 6475-6480, issn 0008-5472, 6 p.Article

Telomerase is regulated by c-Jun NH₂-Terminal kinase in ovarian surface epithelial cellsALFNNSN-DE MATTE, Mirhellp Y; HUA YANG; EVANS, Myria S et al.Cancer research (Baltimore). 2002, Vol 62, Num 16, pp 4575-4578, issn 0008-5472Article

Nitric oxide synthase gene transfer as a tool to study biology of endothelial cellsKATUSIC, Zvonimir S; CAPLICE, Noel M; NATH, Karl A et al.Arteriosclerosis, thrombosis, and vascular biology. 2003, Vol 23, Num 11, pp 1990-1994, issn 1079-5642, 5 p.Article

Evidence for a possible inhibitory interaction between the HO-1/CO-and AKt/NO-pathways in human endothelial cellsBATZLSPERGER, Christian A; ACHATZ, Stefan; SPRENG, Josefine et al.Cardiovascular drugs and therapy. 2007, Vol 21, Num 5, pp 347-355, issn 0920-3206, 9 p.Article

Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cellsCHUN, Kyung-Hee; LEE, Ho-Young; HASSAN, Khaled et al.Cancer research (Baltimore). 2003, Vol 63, Num 16, pp 4796-4800, issn 0008-5472, 5 p.Article

Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/Akt-dependent and MAPK/CREB-independentMIR AHAMED HOSSAIN; RUSSELL, Juliet C; GOMES, Raquel et al.Journal of neurochemistry. 2002, Vol 81, Num 2, pp 365-378, issn 0022-3042Article

Cross-talk between α₄β₁/α₅β₁ and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathwaysKAPUR, Reuben; COOPER, Ryan; LEI ZHANG et al.Blood. 2001, Vol 97, Num 7, pp 1975-1981, issn 0006-4971Article

The AKT kinase is activated in multiple myeloma tumor cellsHSU, Jung-Hsin; YIJIANG SHI; KRAJEWSKI, Stanislaw et al.Blood. 2001, Vol 98, Num 9, pp 2853-2855, issn 0006-4971Article

Akt activation by estrogen in estrogen receptor-negative breast cancer cellsTSAI, Eing-Mei; WANG, Shao-Chun; LEE, Jau-Nan et al.Cancer research (Baltimore). 2001, Vol 61, Num 23, pp 8390-8392, issn 0008-5472Article

Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthaseJIANXIN SUN; LIAO, James K.Arteriosclerosis, thrombosis, and vascular biology. 2004, Vol 24, Num 12, pp 2238-2244, issn 1079-5642, 7 p.Article

Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activityDEGRAFFENRIED, L. A; FRIEDRICHS, W. E; FULCHER, L et al.Annals of oncology. 2003, Vol 14, Num 7, pp 1051-1056, issn 0923-7534, 6 p.Article

Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathwaySITHANANDAM, Gunamani; SMITH, George T; MASUDA, Akira et al.Carcinogenesis (New York. Print). 2003, Vol 24, Num 10, pp 1581-1592, issn 0143-3334, 12 p.Article

Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cellsKANDASAMY, Karthikeyan; SRIVASTAVA, Rakesh K.Cancer research (Baltimore). 2002, Vol 62, Num 17, pp 4929-4937, issn 0008-5472, 9 p.Article

Doxorubicin resistant neuroblastoma cells secrete factors that activate AKT and attenuate cytotoxicity in drug-sensitive cellsEMRAN, Mohammad A; REBBAA, Abdelhadi; MIRKIN, Bernard L et al.Cancer letters. 2002, Vol 182, Num 1, pp 53-59, issn 0304-3835Article

Phosphatidylinositol 3-kinase/akt signaling in the response of vascular endothelium to ionizing radiationEDWARDS, Eric; LING GENG; TAN, J et al.Cancer research (Baltimore). 2002, Vol 62, Num 16, pp 4671-4677, issn 0008-5472Article

Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/akt pathway in glioblastomasNARITA, Yoshitaka; NAGANE, Motoo; MISHIMA, Kazuhiko et al.Cancer research (Baltimore). 2002, Vol 62, Num 22, pp 6764-6769, issn 0008-5472, 6 p.Article

Nitric-oxide-induced Bax integration into the mitochondrial membrane commits MDA-MB-468 cells to apoptosis: Essential role of aktPERVIN, Shehla; SINGH, Rajan; CHAUDHURI, Gautam et al.Cancer research (Baltimore). 2003, Vol 63, Num 17, pp 5470-5479, issn 0008-5472, 10 p.Article

Cyclin D1 over-expression correlates with β-catenin activation, but not with H-ras mutations, and phosphorylation of Akt, GSK3β and ERK1/2 in mouse hepatic carcinogenesisGOTOH, Junichi; OBATA, Masahiko; YOSHIE, Masumi et al.Carcinogenesis (New York. Print). 2003, Vol 24, Num 3, pp 435-442, issn 0143-3334, 8 p.Article

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathwaysTHIMMAIAH, Kuntebommanahalli N; EASTON, John; HUANG, Shile et al.Cancer research (Baltimore). 2003, Vol 63, Num 2, pp 364-374, issn 0008-5472, 11 p.Article